Peptides & Peptide Synthesis Products


Boc-Phe-OH, Catalog No: 48092
(2S)-2-[(2-methylpropan-2-yl)oxycarbonylamino]-3-phenylpropanoic acid, CAS: 13734-34-4, MW: 265.30, Formula: C14H19NO4
Catalog No: 48092
(2S)-2-[(2-methylpropan-2-yl)oxycarbonylamino]-3-phenylpropanoic acid, CAS: 13734-34-4, MW: 265.30, Formula: C14H19NO4


(2S)-2-[(2-methylpropan-2-yl)oxycarbonylamino]-3-phenylpropanoic acid
Additional Information

Additional Information

Catalog Number 48092
CAS 13734-34-4
M.W. 265.30
Formula C14H19NO4
IUPAC Name (2S)-2-[(2-methylpropan-2-yl)oxycarbonylamino]-3-phenylpropanoic acid
Synonym No
Also Known As
  • (2S)-2-[(2-methylpropan-2-yl)oxycarbonylamino]-3-phenylpropanoic acid
  • (2S)-2-(tert-butoxycarbonylamino)-3-phenyl-propanoic acid
  • (2S)-2-[(tert-butoxy-oxomethyl)amino]-3-phenylpropanoic acid
  • (2S)-2-(tert-butoxycarbonylamino)-3-phenyl-propionic acid
  • (2S)-2-[(2-methylpropan-2-yl)oxycarbonylamino]-3-phenyl-propanoic acid
  • 92761-90-5
  • N-((1,1-Dimethylethoxy)carbonyl)-N-L-phenylalanine
  • NSC 111172
  • 15480_ALDRICH
  • 134562_ALDRICH
  • Boc-L-phenylalanine
  • Boc-Phe-OH
  • Alanine, N-carboxy-3-phenyl-, N-tert-butyl ester, L- (8CI)
  • EINECS 237-305-5
  • AIDS-028287
  • AIDS028287
  • N-Boc-L-Phenylalanine
  • Phe-NHBOC
  • L-Phenylalanine, N-((1,1-dimethylethoxy)carbonyl)-
InChI InChI=1S/C14H19NO4/c1-14(2,3)19-13(18)15-11(12(16)17)9-10-7-5-4-6-8-10/h4-8,11H,9H2,1-3H3,(H,15,18)(H,16,17)/t11-/m0/s1
Cited Uses


1. Jida M et al, "One-Pot Isomerization-Cross Metathesis-Reduction (ICMR) Synthesis of Lipophilic Tetrapeptides", ACS combinatorial science, 16(7) pp.342-351 (2014 Jul 14).
2. Wong CT et al, "Realizing serine/threonine ligation: scope and limitations and mechanistic implication thereof", Frontiers in Chemistry, 2() pp.28 ().
3. Zeglis BM et al, "Building Blocks for the Construction of Bioorthogonally Reactive Peptides via Solid-Phase Peptide Synthesis", ChemistryOpen, 3(2) pp.48-53 (2014 Apr).
4. Chen J et al, "Thermo-/pH-dual responsive properties of hyperbranched polyethylenimine grafted by phenylalanine", Archives of Pharmacal Research, 37(1) pp.142-148 (2014).
5. Bandar JS et al, "Cyclopropenimine-Catalyzed Enantioselective Mannich Reactions of t-Butyl Glycinates with N-Boc-Imines", Journal of the American Chemical Society, 135(32) pp.11799-11802 (2013 Aug 14).
6. Tan J et al, "3C Protease of Enterovirus 68: Structure-Based Design of Michael Acceptor Inhibitors and Their Broad-Spectrum Antiviral Effects against Picornaviruses", Journal of Virology, 87(8) pp.4339-4351 (2013 Apr).
7. Novoa A et al, "Variation of the net charge, lipophilicity and side chain flexibility in Dmt1-DALDA: effect on opioid activity and biodistribution", Journal of medicinal chemistry, 55(22) pp.9549-9561 (2012 Nov 26).
8. Sharma LK et al, "Near-Infrared Activity-Based Fluorescent Probe for LMP7: A Chemical Proteomics Tool for Immunoproteasome in Living Cells", Chembiochem : a European journal of chemical biology, 13(13) pp.1899-1903 (2012 Sep 3).
9. Wagner AM et al, "N-Terminal Protein Modification Using Simple Aminoacyl Transferase Substrates", Journal of the American Chemical Society, 133(38) pp.15139-15147 (2011 Sep 28).
10. Hojo K et al, "Development of a method for environmentally friendly chemical peptide synthesis in water using water-dispersible amino acid nanoparticles", Chemistry Central Journal, 5() pp.49 ().
11. Wu X et al, "A novel high-yield synthesis of aminoacyl p-nitroanilines and aminoacyl 7-amino-4-methylcoumarins: Important synthons for the synthesis of chromogenic/fluorogenic protease substrates", Beilstein Journal of Organic Chemistry, 7() pp.1030-1035 ().
12. Thorn K et al, "The tandem chain extension aldol reaction used for synthesis of ketomethylene tripeptidomimetics targeting hPEPT1", Bioorganic & medicinal chemistry letters, 21(15) pp.4597-4601 (2011 Aug 1).
13. Crawford MJ et al, "Effect of Steric Constraint at the γ-Backbone Position on the Conformations and Hybridization Properties of PNAs", Journal of Nucleic Acids, 2011() pp.652702 ().
14. Engle KM et al, "Ligand-Accelerated C-H Activation Reactions: Evidence for a Switch of Mechanism", Journal of the American Chemical Society, 132(40) pp.14137-14151 (2010 Oct 13).
15. Sellers RP et al, "Design and synthesis of Hsp90 Inhibitors: exploring the SAR of Sansalvamide A derivatives", Bioorganic & medicinal chemistry, 18(18) pp.6822-6856 (2010 Sep 15).
16. Newhouse T et al, "Scalable Total Syntheses of N-Linked Tryptamine Dimers by Direct Indole-Aniline Coupling: Psychotrimine and Kapakahines B & F", Journal of the American Chemical Society, 132(20) pp.7119-7137 (2010 May 26).
17. Shi BF et al, "Pd(II)-Catalyzed Enantioselective C-H Olefination of Diphenylacetic Acids", Journal of the American Chemical Society, 132(2) pp.460-461 (2010 Jan 20).
18. Yang Z et al, "Evaluation of ?,?-unsaturated Ketone-based Probes for Papain-Family Cysteine Proteases", Bioorganic & medicinal chemistry, 17(3) pp.1071-1078 (2009 Feb 1).
19. Mollica A et al, "Synthesis of Stable and Potent δ/μ Opioid Peptides: Analogues of H-Tyr-c[D-Cys-Gly-Phe-D-Cys]-OH by Ring-Closing Metathesis", Journal of medicinal chemistry, 50(13) pp.3138-3142 (2007 Jun 28).
20. Yamamoto T et al, "Design, Synthesis, and Biological Evaluation of Novel Bifunctional C-Terminal-Modified Peptides for δ/μ Opioid Receptor Agonists and Neurokinin-1 Receptor Antagonists", Journal of medicinal chemistry, 50(12) pp.2779-2786 (2007 Jun 14).
21. Petrov RR et al, "Synthesis and evaluation of 3-aminopropionyl substituted fentanyl analogues for opioid activity", Bioorganic & medicinal chemistry letters, 16(18) pp.4946-4950 (2006 Sep 15).
22. Reubi JC et al, "SST3-selective potent peptidic somatostatin receptor antagonists", Proceedings of the National Academy of Sciences of the United States of America, 97(25) pp.13973-13978 (2000 Dec 5).
23. Kay G et al, "The synthesis, kinetic characterization and application of biotinylated aminoacylchloromethanes for the detection of chymotrypsin and trypsin-like serine proteinases.", Biochemical Journal, 283(Pt 2) pp.455-459 (1992 Apr 15).
24. Angliker H et al, "The inactivation of the cysteinyl exopeptidases cathepsin H and C by affinity-labelling reagents.", Biochemical Journal, 262(1) pp.63-68 (1989 Aug 15).
25. Angliker H et al, "Synthesis and properties of peptidyl derivatives of arginylfluoromethanes.", Biochemical Journal, 256(2) pp.481-486 (1988 Dec 1).