Peptides & Peptide Synthesis Products

Fmoc-Asn(Trt)-OH

Fmoc-Asn(Trt)-OH

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Fmoc-Asn(Trt)-OH, Catalog No: 41007
Nα-Fmoc-Nγ-trityl-L-asparagine, CAS: 132388-59-1, MW: 596.67, Formula: C38H32N2O5
Catalog No: 41007
Nα-Fmoc-Nγ-trityl-L-asparagine, CAS: 132388-59-1, MW: 596.67, Formula: C38H32N2O5

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Nα-Fmoc-Nγ-trityl-L-asparagine
Additional Information

Additional Information

Catalog Number 41007
CAS 132388-59-1
M.W. 596.67
Formula C38H32N2O5
IUPAC Name (2S)-2-(9H-fluoren-9-ylmethoxycarbonylamino)-4-oxo-4-(tritylamino)butanoic acid
Synonym Nα-Fmoc-Nγ-trityl-L-asparagine
Also Known As
  • (2S)-2-(9H-fluoren-9-ylmethoxycarbonylamino)-4-oxo-4-[tri(phenyl)methylamino]butanoic acid
  • (2S)-2-[(9H-fluoren-9-ylmethoxy-oxomethyl)amino]-4-oxo-4-[tri(phenyl)methylamino]butanoic acid
  • (2S)-2-(9H-fluoren-9-ylmethoxycarbonylamino)-4-keto-4-[tri(phenyl)methylamino]butyric acid
  • Nalpha-Fmoc-Ngamma-trityl-L-asparagine
  • InChI=1/C38H32N2O5/c41-35(40-38(26-14-4-1-5-15-26,27-16-6-2-7-17-27)28-18-8-3-9-19-28)24-34(36(42)43)39-37(44)45-25-33-31-22-12-10-20-29(31)30-21-11-13-23-32(30)33/h1-23,33-34H,24-25H2,(H,39,44)(H,40,41)(H,42,43
  • N~2~-[(9H-fluoren-9-ylmethoxy)carbonyl]-N-tritylasparagine
  • asparagine, N~2~-[(9H-fluoren-9-ylmethoxy)carbonyl]-N-(triphenylmethyl)-
  • 47672_FLUKA
  • Fmoc-Asn(Trt)-OH
  • Nalpha-(9-Fluorenylmethoxycarbonyl)-Ngamma-trityl-L-asparagine
  • SBB005414
InChIKey KJYAFJQCGPUXJY-UMSFTDKQSA-N
InChI InChI=1S/C38H32N2O5/c41-35(40-38(26-14-4-1-5-15-26,27-16-6-2-7-17-27)28-18-8-3-9-19-28)24-34(36(42)43)39-37(44)45-25-33-31-22-12-10-20-29(31)30-21-11-13-23-32(30)33/h1-23,33-34H,24-25H2,(H,39,44)(H,40,41)(H,42,43)/t34-/m0/s1
SMILES C1=CC=C(C=C1)C(C2=CC=CC=C2)(C3=CC=CC=C3)NC(=O)C[C@@H](C(=O)O)NC(=O)OCC4C5=CC=CC=C5C6=CC=CC=C46
Cited Uses

Details

1. Pipkorn R et al, "A Peptide & Peptide Nucleic Acid Synthesis Technology for Transporter Molecules and Theranostics - The SPPS", International Journal of Medical Sciences, 11(7) pp.697-706 ().
2. Giltrap AM et al, "Total Synthesis of Fellutamide B and Deoxy-Fellutamides B, C, and D", Marine Drugs, 11(7) pp.2382-2397 ().
3. Amin MN et al, "Synthetic glycopeptides reveal the glycan specificity of HIV-neutralizing antibodies", Nature chemical biology, 9(8) pp.521-526 (2013 Aug).
4. Chen W et al, "The Structural and Energetic Basis of Carbohydrate Aromatic Packing Interactions in Proteins", Journal of the American Chemical Society, 135(26) pp.9877-9884 (2013 Jul 3).
5. Neupane KP et al, "Macrocyclization of the ATCUN Motif Controls Metal Binding and Catalysis", Inorganic chemistry, 52(5) pp.2729-2735 (2013 Mar 4).
6. Gunasekera S et al, "Making Ends Meet: Microwave-Accelerated Synthesis of Cyclic and Disulfide Rich Proteins Via In Situ Thioesterification and Native Chemical Ligation", International Journal of Peptide Research and Therapeutics, 19(1) pp.43-54 (2013 Mar).
7. Wu X et al, "Synthesis and evaluation of a peptide targeted small molecular Gd-DOTA monoamide conjugate for MR molecular imaging of prostate cancer", Bioconjugate chemistry, 23(8) pp.1548-1556 (2012 Aug 15).
8. Tatsi A et al, "[111In-DOTA]Somatostatin-14 analogs as potential pansomatostatin-like radiotracers - first results of a preclinical study", EJNMMI Research, 2() pp.25 ().
9. Batjargal S et al, "Native Chemical Ligation of Thioamide-Containing Peptides: Development and Application to the Synthesis of Labeled ?-Synuclein for Misfolding Studies", Journal of the American Chemical Society, 134(22) pp.9172-9182 (2012 Jun 6).
10. Li Y et al, "Opioid glycopeptide analgesics derived from endogenous enkephalins and endorphins", Future Medicinal Chemistry, 4(2) pp.205-226 (2012 Feb).
11. Rothbart SB et al, "Peptide Microarrays to Interrogate the Histone Code", Methods in enzymology, 512() pp.107-135 (2012).
12. Dong S et al, "Toward Homogeneous Erythropoietin: Application of Metal Free Dethiylation in the Chemical Synthesis of the Ala79-Arg166 Glycopeptide Domain", Israel journal of chemistry, 51(8-9) pp.968-976 (2011 Nov).
13. Kaushansky A et al, "Quantifying protein-protein interactions in high throughput using protein domain microarrays", Nature protocols, 5(4) pp.773-790 (2010).
14. Negussie AH et al, "Synthesis and in vitro evaluation of cyclic NGR peptide targeted thermally sensitive liposome", Journal of controlled release : official journal of the Controlled Release Society, 143(2) pp.265-273 (2010 Apr 19).
15. Capparelli R et al, "Synergistic Antibacterial and Anti-Inflammatory Activity of Temporin A and Modified Temporin B In Vivo", PLoS ONE, 4(9) pp.e7191 ().
16. Ndinguri MW et al, "PEPTIDE TARGETING OF PLATINUM ANTI-CANCER DRUGS", Bioconjugate chemistry, 20(10) pp.1869-1878 (2009 Oct 21).
17. Van de Vijver P et al, "Synthetic Microcin C Analogs Targeting Different Aminoacyl-tRNA Synthetases", Journal of Bacteriology, 191(20) pp.6273-6280 (2009 Oct).
18. Jagasia R et al, "Peptide Cyclization and Cyclodimerization by CuI-Mediated Azide-Alkyne Cycloaddition", The Journal of organic chemistry, 74(8) pp.2964-2974 (2009 Apr 17).
19. Schneider EL et al, "Positional Scanning Synthetic Combinatorial Libraries for Substrate Profiling", Methods in molecular biology (Clifton, N.J.), 539() pp.59-78 (2009).
20. Gareiss PC et al, "Dynamic Combinatorial Selection of Molecules Capable of Inhibiting the (CUG) Repeat RNA - MBNL1 Interaction in vitro: Discovery of Lead Compounds Targeting Myotonic Dystrophy (DM1)", Journal of the American Chemical Society, 130(48) pp.16254-16261 (2008 Dec 3).
21. Dong M et al, "Exploration of the Endogenous Agonist Mechanism for Activation of Secretin and VPAC1 Receptors Using Synthetic Glycosylated Peptides", Journal of molecular neuroscience : MN, 36(0) pp.10.1007/s12031-008-9058-6 (2008 Nov).
22. Mukhopadhyay S et al, "Conjugated Platinum(IV)-Peptide Complexes for Targeting Angiogenic Tumor Vasculature", Bioconjugate chemistry, 19(1) pp.39-49 (2008 Jan).
23. Nam J et al, "Alanine Scan of [L-Dap2]Ramoplanin A2 Aglycon: Assessment of the Importance of Each Residue", Journal of the American Chemical Society, 129(28) pp.8747-8755 (2007 Jul 18).
24. Niyomrattanakit P et al, "Probing the substrate specificity of the dengue virus type 2 NS3 serine protease by using internally quenched fluorescent peptides", Biochemical Journal, 397(Pt 1) pp.203-211 (2006 Jul 1).
25. Schneekloth JS Jr et al, "Neurotrophic peptide aldehydes: Solid phase synthesis of fellutamide B and a simplified analog", Bioorganic & medicinal chemistry letters, 16(14) pp.3855-3858 (2006 Jul 15).
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