Peptides & Peptide Synthesis Products

Fmoc-Glu-OAll

Fmoc-Glu-OAll

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Fmoc-Glu-OAll, Catalog No: 41070
Nα-Fmoc-L-glutamic acid α-allyl ester, CAS: 144120-54-7, MW: 409.43, Formula: C23H23NO6
Catalog No: 41070
Nα-Fmoc-L-glutamic acid α-allyl ester, CAS: 144120-54-7, MW: 409.43, Formula: C23H23NO6
Description

Details

Nα-Fmoc-L-glutamic acid α-allyl ester
Additional Information

Additional Information

Catalog Number 41070
CAS 144120-54-7
M.W. 409.43
Formula C23H23NO6
IUPAC Name (4S)-4-(9H-fluoren-9-ylmethoxycarbonylamino)-5-oxo-5-prop-2-enoxypentanoic acid
Synonym Nα-Fmoc-L-glutamic acid α-allyl ester
Also Known As
  • (4S)-4-(9H-fluoren-9-ylmethoxycarbonylamino)-5-oxo-5-prop-2-enoxypentanoic acid
  • (4S)-5-allyloxy-4-(9H-fluoren-9-ylmethoxycarbonylamino)-5-oxo-pentanoic acid
  • (4S)-5-allyloxy-4-[(9H-fluoren-9-ylmethoxy-oxomethyl)amino]-5-oxopentanoic acid
  • (4S)-5-allyloxy-4-(9H-fluoren-9-ylmethoxycarbonylamino)-5-keto-valeric acid
  • (4S)-4-(9H-fluoren-9-ylmethoxycarbonylamino)-5-oxo-5-prop-2-enoxy-pentanoic acid
  • Fmoc-Glu-OAll
  • Fmoc-L-glutamic acid 1-allyl ester
  • 47702_FLUKA
InChIKey ORKKMGRINLTBPC-FQEVSTJZSA-N
InChI InChI=1S/C23H23NO6/c1-2-13-29-22(27)20(11-12-21(25)26)24-23(28)30-14-19-17-9-5-3-7-15(17)16-8-4-6-10-18(16)19/h2-10,19-20H,1,11-14H2,(H,24,28)(H,25,26)/t20-/m0/s1
SMILES C=CCOC(=O)[C@H](CCC(=O)O)NC(=O)OCC1C2=CC=CC=C2C3=CC=CC=C13
Cited Uses

Details

1. Thakkar A et al, "Global Analysis of Peptide Cyclization Efficiency", ACS combinatorial science, 15(2) pp.120-129 (2013 Feb 11).
2. Wu X et al, "Inhibition of Ras-Effector Interaction by Cyclic Peptides", MedChemComm, 4(2) pp.378-382 (2013 Feb 1).
3. Quartararo JS et al, "Peptide Bicycles that Inhibit the Grb2 SH2 Domain", Chembiochem : a European journal of chemical biology, 13(10) pp.1490-1496 (2012 Jul 9).
4. Dewan V et al, "Cyclic Peptide Inhibitors of HIV-1 Capsid-Human Lysyl-tRNA Synthetase Interaction", ACS Chemical Biology, 7(4) pp.761-769 (2012 Apr 20).
5. Yan Y et al, "Peptide heterodimers for molecular imaging", Amino acids, 41(5) pp.1081-1092 (2011 Nov).
6. Negussie AH et al, "Synthesis and in vitro evaluation of cyclic NGR peptide targeted thermally sensitive liposome", Journal of controlled release : official journal of the Controlled Release Society, 143(2) pp.265-273 (2010 Apr 19).
7. Zhu J et al, "Design and Synthesis of Biomimetic Hydrogel Scaffolds with Controlled Organization of Cyclic RGD Peptides", Bioconjugate chemistry, 20(2) pp.333-339 (2009 Feb).
8. Shiraishi T et al, "Subnanomolar antisense activity of phosphonate-peptide nucleic acid (PNA) conjugates delivered by cationic lipids to HeLa cells", Nucleic Acids Research, 36(13) pp.4424-4432 (2008 Aug).
9. Zhu J et al, "Solid-Phase Synthesis of Tailed Cyclic RGD Peptides Using Glutamic Acid: Unexpected Glutarimide Formation", Journal of Peptide Science, 14(6) pp.690-696 (2008 Jun).
10. Mayorov AV et al, "Development of Cyclic ?-MSH Analogues with Selective hMC3R Agonist and hMC3R/hMC5R Antagonist Activities", Journal of medicinal chemistry, 49(6) pp.1946-1952 (2006 Mar 23).
11. Van Dijk AA et al, "Structure characterization of the central repetitive domain of high molecular weight gluten proteins. I. Model studies using cyclic and linear peptides.", Protein Science : A Publication of the Protein Society, 6(3) pp.637-648 (1997 Mar).
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