Peptides & Peptide Synthesis Products

Fmoc-Glu(OtBu)-OH

Fmoc-Glu(OtBu)-OH
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Fmoc-Glu(OtBu)-OH, Catalog No: 41005
Nα-Fmoc-L-glutamic acid 5-tert-butyl ester, CAS: 71989-18-9, MW: 425.47, Formula: C24H27NO6
Catalog No: 41005
Nα-Fmoc-L-glutamic acid 5-tert-butyl ester, CAS: 71989-18-9, MW: 425.47, Formula: C24H27NO6

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Description

Details

Nα-Fmoc-L-glutamic acid 5-tert-butyl ester
Additional Information

Additional Information

Catalog Number 41005
CAS 71989-18-9
M.W. 425.47
Formula C24H27NO6
IUPAC Name 2-(9H-fluoren-9-ylmethoxycarbonylamino)-5-[(2-methylpropan-2-yl)oxy]-5-oxopentanoic acid
Synonym Nα-Fmoc-L-glutamic acid 5-tert-butyl ester
Also Known As
  • 2-(9H-fluoren-9-ylmethoxycarbonylamino)-5-[(2-methylpropan-2-yl)oxy]-5-oxopentanoic acid
  • 5-tert-butoxy-2-(9H-fluoren-9-ylmethoxycarbonylamino)-5-oxo-pentanoic acid
  • 5-tert-butoxy-2-[(9H-fluoren-9-ylmethoxy-oxomethyl)amino]-5-oxopentanoic acid
  • 5-tert-butoxy-2-(9H-fluoren-9-ylmethoxycarbonylamino)-5-keto-valeric acid
  • 2-(9H-fluoren-9-ylmethoxycarbonylamino)-5-[(2-methylpropan-2-yl)oxy]-5-oxo-pentanoic acid
InChIKey OTKXCALUHMPIGM-UHFFFAOYSA-N
InChI InChI=1S/C24H27NO6/c1-24(2,3)31-21(26)13-12-20(22(27)28)25-23(29)30-14-19-17-10-6-4-8-15(17)16-9-5-7-11-18(16)19/h4-11,19-20H,12-14H2,1-3H3,(H,25,29)(H,27,28)
SMILES CC(C)(C)OC(=O)CCC(C(=O)O)NC(=O)OCC1C2=CC=CC=C2C3=CC=CC=C13
Cited Uses

Details

1. Thakkar A et al, "Global Analysis of Peptide Cyclization Efficiency", ACS combinatorial science, 15(2) pp.120-129 (2013 Feb 11).
2. Bahta M et al, "Oxime-based linker libraries as a general approach for the rapid generation and screening of multidentate inhibitors", Nature protocols, 7(4) pp.686-702 ().
3. Tegge W et al, "Synthesis of Peptides from α- and β-Tubulin Containing Glutamic Acid Side-Chain Linked Oligo-Glu with Defined Length", International Journal of Peptides, 2010() pp.189396 (2010).
4. Mandal PK et al, "Structure-Affinity Relationships of Glutamine Mimics Incorporated into Phosphopeptides Targeted to the SH2 Domain of Signal Transducer and Activator of Transcription 3", Journal of medicinal chemistry, 52(19) pp.6126-6141 (2009 Oct 8).
5. Ye G et al, "Synthesis and Evaluation of Phosphopeptides Containing Iminodiacetate Groups as Binding Ligands of the Src SH2 Domain", Bioorganic chemistry, 37(4) pp.133-142 (2009 Aug).
6. Mandal PK et al, "Conformationally Constrained Peptidomimetic Inhibitors of Signal Transducer and Activator of Transcription 3: Evaluation and Molecular Modeling", Journal of medicinal chemistry, 52(8) pp.2429-2442 (2009 Apr 23).
7. Anderson MO et al, "Substrate Specificity of Prostate-Specific Membrane Antigen", Bioorganic & medicinal chemistry, 15(21) pp.6678-6686 (2007 Nov 1).
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