Peptides & Peptide Synthesis Products


Fmoc-Leu-OH, Catalog No: 41003
Nα-Fmoc-L-leucine, CAS: 35661-60-0, MW: 353.41, Formula: C21H23NO4
Catalog No: 41003
Nα-Fmoc-L-leucine, CAS: 35661-60-0, MW: 353.41, Formula: C21H23NO4

* Required Fields



Additional Information

Additional Information

Catalog Number 41003
CAS 35661-60-0
M.W. 353.41
Formula C21H23NO4
IUPAC Name (2S)-2-(9H-fluoren-9-ylmethoxycarbonylamino)-4-methylpentanoic acid
Synonym Nα-Fmoc-L-leucine
Also Known As
  • (2S)-2-(9H-fluoren-9-ylmethoxycarbonylamino)-4-methylpentanoic acid
  • (2S)-2-(9H-fluoren-9-ylmethoxycarbonylamino)-4-methyl-pentanoic acid
  • (2S)-2-[(9H-fluoren-9-ylmethoxy-oxomethyl)amino]-4-methylpentanoic acid
  • (2S)-2-(9H-fluoren-9-ylmethoxycarbonylamino)-4-methyl-valeric acid
  • CDS1_000810
  • DivK1c_001850
  • NCGC00164403-01
  • 408611_ALDRICH
  • Fmoc-Leu-OH
  • ST5307349
  • Maybridge1_005562
  • 47633_FLUKA
InChI InChI=1S/C21H23NO4/c1-13(2)11-19(20(23)24)22-21(25)26-12-18-16-9-5-3-7-14(16)15-8-4-6-10-17(15)18/h3-10,13,18-19H,11-12H2,1-2H3,(H,22,25)(H,23,24)/t19-/m0/s1
Cited Uses


1. Abbate V et al, "Manipulating the pH response of 2,3-diaminopropionic acid rich peptides to mediate highly effective gene silencing with low-toxicity", Journal of Controlled Release, 172(3) pp.929-938 (2013 Dec 28).
2. Wu X et al, "Identification of a novel peptide that blocks basic fibroblast growth factor-mediated cell proliferation", Oncotarget, 4(10) pp.1819-1828 ().
3. Witte MD et al, "Production of unnaturally linked chimeric proteins using a combination of sortase-catalyzed transpeptidation and click chemistry", Nature protocols, 8(9) pp.1808-1819 (2013 Sep).
4. Theile CS et al, "Site-specific N-terminal labeling of proteins using sortase-mediated reactions", Nature protocols, 8(9) pp.1800-1807 (2013 Sep).
5. Wang W et al, "Loss of Apelin Exacerbates Myocardial Infarction Adverse Remodeling and Ischemia-reperfusion Injury: Therapeutic Potential of Synthetic Apelin Analogues", Journal of the American Heart Association: Cardiovascular and Cerebrovascular Disease, 2(4) pp.e000249 ().
6. Giltrap AM et al, "Total Synthesis of Fellutamide B and Deoxy-Fellutamides B, C, and D", Marine Drugs, 11(7) pp.2382-2397 ().
7. Bąchor R et al, "New method of peptide cleavage based on Edman degradation", Molecular Diversity, 17(3) pp.605-611 (2013 Aug).
8. Rochon K et al, "Preparation and Evaluation at the Delta Opioid Receptor of a Series of Linear Leu-Enkephalin Analogues Obtained by Systematic Replacement of the Amides", ACS Chemical Neuroscience, 4(8) pp.1204-1216 ().
9. Wissner RF et al, "Labeling Proteins with Fluorophore/Thioamide FRET Pairs by Combining Unnatural Amino Acid Mutagenesis and Native Chemical Ligation", Journal of the American Chemical Society, 135(17) pp.6529-6540 (2013 May 1).
10. Shirazi AN et al, "Efficient Delivery of Cell Impermeable Phosphopeptides by a Cyclic Peptide Amphiphile Containing Tryptophan and Arginine", Molecular pharmaceutics, 10(5) pp.2008-2020 (2013 May 6).
11. Neupane KP et al, "Macrocyclization of the ATCUN Motif Controls Metal Binding and Catalysis", Inorganic chemistry, 52(5) pp.2729-2735 (2013 Mar 4).
12. Li Y et al, "18F-click labeling of a bombesin antagonist with an alkyne-18F-ArBF3 -: in vivo PET imaging of tumors expressing the GRP-receptor", American Journal of Nuclear Medicine and Molecular Imaging, 3(1) pp.57-70 ().
13. Güell I et al, "Multivalent display of the antimicrobial peptides BP100 and BP143", Beilstein Journal of Organic Chemistry, 8() pp.2106-2117 ().
14. Chen PC et al, "DNA-Interactive Properties of Crotamine, a Cell-Penetrating Polypeptide and a Potential Drug Carrier", PLoS ONE, 7(11) pp.e48913 ().
15. Gunasekera S et al, "Making Ends Meet: Microwave-Accelerated Synthesis of Cyclic and Disulfide Rich Proteins Via In Situ Thioesterification and Native Chemical Ligation", International Journal of Peptide Research and Therapeutics, 19(1) pp.43-54 (2013 Mar).
16. Huang J et al, "Residue analysis of a CTL epitope of SARS-CoV spike protein by IFN-gamma production and bioinformatics prediction", BMC Immunology, 13() pp.50 ().
17. Wu X et al, "Synthesis and evaluation of a peptide targeted small molecular Gd-DOTA monoamide conjugate for MR molecular imaging of prostate cancer", Bioconjugate chemistry, 23(8) pp.1548-1556 (2012 Aug 15).
18. Khattab SN et al, "Screening of N-Alkyl-Cyanoacetamido Oximes as Substitutes for N-Hydroxysuccinimide", ChemistryOpen, 1(3) pp.147-152 (2012 Jun).
19. Knerr PJ et al, "Chemical Synthesis and Biological Activity of Analogues of the Lantibiotic Epilancin 15X", Journal of the American Chemical Society, 134(18) pp.7648-7651 (2012 May 9).
20. Batjargal S et al, "Native Chemical Ligation of Thioamide-Containing Peptides: Development and Application to the Synthesis of Labeled ?-Synuclein for Misfolding Studies", Journal of the American Chemical Society, 134(22) pp.9172-9182 (2012 Jun 6).
21. Li YJ et al, "Gold nanoparticles as a platform for creating a multivalent poly-SUMO chain inhibitor that also augments ionizing radiation", Proceedings of the National Academy of Sciences of the United States of America, 109(11) pp.4092-4097 (2012 Mar 13).
22. Davis MR et al, "Synthesis of sansalvamide A peptidomimetics: triazole, oxazole, thiazole, and pseudoproline containing compounds", Tetrahedron, 68(4) pp.1029-1051 (2012 Jan 28).
23. Rothbart SB et al, "Peptide Microarrays to Interrogate the Histone Code", Methods in enzymology, 512() pp.107-135 (2012).
24. van der Linden WA et al, "Discovery of a potent and highly β1 specific proteasome inhibitor from a focused library of urea-containing peptide vinyl sulfones and peptide epoxyketones", Organic & biomolecular chemistry, 10(1) pp.181-194 (2012 Jan 7).
25. Wasa M et al, "Pd(II)-Catalyzed Enantioselective C-H Activation of Cyclopropanes", Journal of the American Chemical Society, 133(49) pp.19598-19601 (2011 Dec 14).