Peptides & Peptide Synthesis Products


Fmoc-Met-OH, Catalog No: 41020
Nα-Fmoc-L-methionine, CAS: 71989-28-1, MW: 371.45, Formula: C20H21NO4S
Catalog No: 41020
Nα-Fmoc-L-methionine, CAS: 71989-28-1, MW: 371.45, Formula: C20H21NO4S

* Required Fields



Additional Information

Additional Information

Catalog Number 41020
CAS 71989-28-1
M.W. 371.45
Formula C20H21NO4S
IUPAC Name (2S)-2-(9H-fluoren-9-ylmethoxycarbonylamino)-4-methylsulfanylbutanoic acid
Synonym Nα-Fmoc-L-methionine
Also Known As
  • (2S)-2-(9H-fluoren-9-ylmethoxycarbonylamino)-4-methylsulfanylbutanoic acid
  • (2S)-2-(9H-fluoren-9-ylmethoxycarbonylamino)-4-methylsulfanyl-butanoic acid
  • (2S)-2-[(9H-fluoren-9-ylmethoxy-oxomethyl)amino]-4-(methylthio)butanoic acid
  • (2S)-2-(9H-fluoren-9-ylmethoxycarbonylamino)-4-(methylthio)butyric acid
  • Fmoc-L-methionine
  • SBB001426
  • Fmoc-Met-OH
  • 47634_FLUKA
InChI InChI=1S/C20H21NO4S/c1-26-11-10-18(19(22)23)21-20(24)25-12-17-15-8-4-2-6-13(15)14-7-3-5-9-16(14)17/h2-9,17-18H,10-12H2,1H3,(H,21,24)(H,22,23)/t18-/m0/s1
Cited Uses


1. Wong CT et al, "Realizing serine/threonine ligation: scope and limitations and mechanistic implication thereof", Frontiers in Chemistry, 2() pp.28 ().
2. Wissner RF et al, "Labeling Proteins with Fluorophore/Thioamide FRET Pairs by Combining Unnatural Amino Acid Mutagenesis and Native Chemical Ligation", Journal of the American Chemical Society, 135(17) pp.6529-6540 (2013 May 1).
3. Gao Y et al, "Synthesis, Screening and Hit Optimization of Stereochemically Diverse Combinatorial Libraries of Peptide Tertiary Amides", Chemistry & biology, 20(3) pp.10.1016/j.chembiol.2013.01.013 (2013 Mar 21).
4. Kunys AR et al, "Specificity Profiling of Protein-Binding Domains Using One-Bead-One-Compound Peptide Libraries", Current protocols in chemical biology, 4(4) pp.331-355 (2012 Dec 1).
5. Liu X et al, "Rapid Development of a Potent Photo-Triggered Inhibitor of the Serine Hydrolase RBBP9", Chembiochem : a European journal of chemical biology, 13(14) pp.2082-2093 (2012 Sep 24).
6. Batjargal S et al, "Native Chemical Ligation of Thioamide-Containing Peptides: Development and Application to the Synthesis of Labeled ?-Synuclein for Misfolding Studies", Journal of the American Chemical Society, 134(22) pp.9172-9182 (2012 Jun 6).
7. Rothbart SB et al, "Peptide Microarrays to Interrogate the Histone Code", Methods in enzymology, 512() pp.107-135 (2012).
8. Napolitano R et al, "On-bead combinatorial synthesis and imaging of CEST-MRI agents to identify factors that influence water exchange", Journal of the American Chemical Society, 133(33) pp.13023-13030 (2011 Aug 24).
9. Bicker KL et al, "Boronic acid functionalized peptidyl synthetic lectins: Combinatorial library design, peptide sequencing, and selective glycoprotein recognition", ACS combinatorial science, 13(3) pp.232-243 (2011 May 9).
10. Lowery CA et al, "Medicinal Chemistry as a Conduit for the Modulation of Quorum Sensing", Journal of medicinal chemistry, 53(21) pp.7467-7489 (2010 Nov 11).
11. Xiao Q et al, "Protein N-Terminal Processing: Substrate Specificity of Escherichia coli and Human Methionine Aminopeptidases", Biochemistry, 49(26) pp.5588-5599 (2010 Jul 6).
12. Kaushansky A et al, "Quantifying protein-protein interactions in high throughput using protein domain microarrays", Nature protocols, 5(4) pp.773-790 (2010).
13. Bern M et al, "Conversion of Methionine to Homocysteic Acid in Heavily Oxidized Proteomics Samples", Rapid communications in mass spectrometry : RCM, 24(6) pp.768-772 (2010 Mar).
14. Qi X et al, "Rapid Identification of Orexin Receptor Binding Ligands Using Cell-Based Screening Accelerated with Magnetic Beads", Molecular Biosystems, 6(1) pp.102-107 (2010 Jan).
15. Jagasia R et al, "Peptide Cyclization and Cyclodimerization by CuI-Mediated Azide-Alkyne Cycloaddition", The Journal of organic chemistry, 74(8) pp.2964-2974 (2009 Apr 17).
16. Schneider EL et al, "Positional Scanning Synthetic Combinatorial Libraries for Substrate Profiling", Methods in molecular biology (Clifton, N.J.), 539() pp.59-78 (2009).
17. Chen X et al, "On-Bead Screening of Combinatorial Libraries: Reduction of Nonspecific Binding by Decreasing Surface Ligand Density", Journal of combinatorial chemistry, 11(4) pp.604-611 (2009).
18. Breitung ST et al, "A practical synthesis of the 13C/15N-labelled tripeptide N-formyl-Met-Leu-Phe, useful as a reference in solid-state NMR spectroscopy", Beilstein Journal of Organic Chemistry, 4() pp.35 ().
19. Xiao Q et al, "High-Throughput Synthesis and Screening of Cyclic Peptide Antibiotics", Journal of medicinal chemistry, 50(13) pp.3132-3137 (2007 Jun 28).
20. Niyomrattanakit P et al, "Probing the substrate specificity of the dengue virus type 2 NS3 serine protease by using internally quenched fluorescent peptides", Biochemical Journal, 397(Pt 1) pp.203-211 (2006 Jul 1).
21. Tsubery H et al, "Neopeptide Antibiotics That Function as Opsonins and Membrane-Permeabilizing Agents for Gram-Negative Bacteria", Antimicrobial Agents and Chemotherapy, 49(8) pp.3122-3128 (2005 Aug).
22. Harris JL et al, "Rapid and general profiling of protease specificity by using combinatorial fluorogenic substrate libraries", Proceedings of the National Academy of Sciences of the United States of America, 97(14) pp.7754-7759 (2000 Jul 5).
23. Jayawickreme CK et al, "Creation and functional screening of a multi-use peptide library.", Proceedings of the National Academy of Sciences of the United States of America, 91(5) pp.1614-1618 (1994 Mar 1).