Peptides & Peptide Synthesis Products

Fmoc-Nle-OH

Fmoc-Nle-OH
$38.00
$38.00
Fmoc-Nle-OH, Catalog No: 47182
Fmoc-L-2-aminohexanoic acid, CAS: 77284-32-3, MW: 353.41, Formula: C21H23NO4
Catalog No: 47182
Fmoc-L-2-aminohexanoic acid, CAS: 77284-32-3, MW: 353.41, Formula: C21H23NO4
Description

Details

Fmoc-L-2-aminohexanoic acid
Additional Information

Additional Information

Catalog Number 47182
CAS 77284-32-3
M.W. 353.41
Formula C21H23NO4
IUPAC Name (2S)-2-(9H-fluoren-9-ylmethoxycarbonylamino)hexanoic acid
Synonym Fmoc-L-2-aminohexanoic acid
Also Known As
  • (2S)-2-(9H-fluoren-9-ylmethoxycarbonylamino)hexanoic acid
  • (2S)-2-[(9H-fluoren-9-ylmethoxy-oxomethyl)amino]hexanoic acid
  • (S)-2-(Fmoc-amino)caproic acid
  • (S)-2-(Fmoc-amino)hexanoic acid
  • 459291_ALDRICH
  • Fmoc-L-norleucine
  • Fmoc-Nle-OH
  • N-(9-Fluorenylmethoxycarbonyl)-L-norleucine
  • 47692_FLUKA
  • 2′,7′-Dichlorofluorescein diacetate
  • 35845_FLUKA
InChIKey VCFCFPNRQDANPN-IBGZPJMESA-N
InChI InChI=1S/C21H23NO4/c1-2-3-12-19(20(23)24)22-21(25)26-13-18-16-10-6-4-8-14(16)15-9-5-7-11-17(15)18/h4-11,18-19H,2-3,12-13H2,1H3,(H,22,25)(H,23,24)/t19-/m0/s1
SMILES CCCC[C@@H](C(=O)O)NC(=O)OCC1C2=CC=CC=C2C3=CC=CC=C13
Cited Uses

Details

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2. Sato M et al, "Site-specific Inhibitory Mechanism for Amyloid ?42 Aggregation by Catechol-type Flavonoids Targeting the Lys Residues", The Journal of Biological Chemistry, 288(32) pp.23212-23224 (2013 Aug 9).
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6. Mahto SK et al, "A Reversible Protection Strategy to Improve Fmoc-SPPS of Peptide Thioesters by the N-Acylurea Approach", Chembiochem : a European journal of chemical biology, 12(16) pp.2488-2494 (2011 Nov 4).
7. Yamamoto T et al, "Biological and Conformational Evaluation of Bifunctional Compounds for Opioid Receptor Agonists and Neurokinin 1 Receptor Antagonists Possessing Two Penicillamines", Journal of medicinal chemistry, 53(15) pp.5491-5501 (2010 Aug 12).
8. Doedens L et al, "Multiple N-methylation of MT-II backbone amide bonds leads to melanocortin receptor subtype hMC1R selectivity; pharmacological and conformational studies", Journal of the American Chemical Society, 132(23) pp.8115-8128 (2010 Jun 16).
9. Verdoes M et al, "A panel of subunit-selective activity-based proteasome probes", Organic & biomolecular chemistry, 8(12) pp.2719-2727 (2010 Jun 21).
10. Yamamoto T et al, "Improving Metabolic Stability By Glycosylation: Bifunctional Peptide Derivatives That Are Opioid Receptor Agonists and Neurokinin 1 Receptor Antagonists", Journal of medicinal chemistry, 52(16) pp.5164-5175 (2009 Aug 27).
11. Yamamoto T et al, "The Biological Activity and Metabolic Stability of Peptidic Bifunctional Compounds That Are Opioid Receptor Agonists and Neurokinin 1 Receptor Antagonists with A Cystine Moiety", Bioorganic & medicinal chemistry, 17(20) pp.7337-7343 (2009 Oct 15).
12. Qu H et al, "Substitution of Arginine with Proline and Proline Derivatives in Melanocyte-Stimulating Hormones Leads to Selectivity for Human Melanocortin 4 Receptor", Journal of medicinal chemistry, 52(12) pp.3627-3635 (2009 Jun 25).
13. Schneider EL et al, "Positional Scanning Synthetic Combinatorial Libraries for Substrate Profiling", Methods in molecular biology (Clifton, N.J.), 539() pp.59-78 (2009).
14. Harris JL et al, "Rapid and general profiling of protease specificity by using combinatorial fluorogenic substrate libraries", Proceedings of the National Academy of Sciences of the United States of America, 97(14) pp.7754-7759 (2000 Jul 5).
15. Bunin BA et al, "The combinatorial synthesis and chemical and biological evaluation of a 1,4-benzodiazepine library.", Proceedings of the National Academy of Sciences of the United States of America, 91(11) pp.4708-4712 (1994 May 24).
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