Peptides & Peptide Synthesis Products


HCTU, Catalog No: 31003
O-(6-Chlorobenzotriazol-1-yl)-N,N,N′,N′-tetramethyluronium hexafluorophosphate, CAS: 330645-87-9, MW: 413.69, Formula: C11H15ClF6N5OP
Catalog No: 31003
O-(6-Chlorobenzotriazol-1-yl)-N,N,N′,N′-tetramethyluronium hexafluorophosphate, CAS: 330645-87-9, MW: 413.69, Formula: C11H15ClF6N5OP

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O-(6-Chlorobenzotriazol-1-yl)-N,N,N′,N′-tetramethyluronium hexafluorophosphate
Additional Information

Additional Information

Catalog Number 31003
CAS 330645-87-9
M.W. 413.69
Formula C11H15ClF6N5OP
IUPAC Name [(6-chlorobenzotriazol-1-yl)oxy-(dimethylamino)methylidene]-dimethylazanium;hexafluorophosphate
Synonym O-(6-Chlorobenzotriazol-1-yl)-N,N,N′,N′-tetramethyluronium hexafluorophosphate
Also Known As No
InChI InChI=1S/C11H15ClN5O.F6P/c1-15(2)11(16(3)4)18-17-10-7-8(12)5-6-9(10)13-14-17;1-7(2,3,4,5)6/h5-7H,1-4H3;/q+1;-1
SMILES CN(C)C(=[N+](C)C)ON1C2=C(C=CC(=C2)Cl)N=N1.F[P-](F)(F)(F)(F)F
Cited Uses


1. Willems MM et al, "Design, automated synthesis and immunological evaluation of NOD2-ligand-antigen conjugates", Beilstein Journal of Organic Chemistry, 10() pp.1445-1453 ().
2. Obermeyer AC et al, "Multivalent Viral Capsids with Internal Cargo for Fibrin Imaging", PLoS ONE, 9(6) pp.e100678 ().
3. Nguyen B et al, "Characterization of a Novel Conus bandanus Conopeptide Belonging to the M-Superfamily Containing Bromotryptophan", Marine Drugs, 12(6) pp.3449-3465 ().
4. Lee CJ et al, "Cathelicidin LL-37 and HSV-1 Corneal Infection: Peptide Versus Gene Therapy", Translational Vision Science & Technology, 3(3) pp.4 ().
5. Pravetoni M et al, "Effect of Currently Approved Carriers and Adjuvants on the Pre-Clinical Efficacy of a Conjugate Vaccine against Oxycodone in Mice and Rats", PLoS ONE, 9(5) pp.e96547 ().
6. Borodkin VS et al, "Bisubstrate UDP-peptide conjugates as human O-GlcNAc transferase inhibitors", Biochemical Journal, 457(Pt 3) pp.497-502 (2014 Feb 1).
7. Abbate V et al, "Manipulating the pH response of 2,3-diaminopropionic acid rich peptides to mediate highly effective gene silencing with low-toxicity", Journal of Controlled Release, 172(3) pp.929-938 (2013 Dec 28).
8. Zhang H et al, "Dual-acting stapled peptides target both HIV-1 entry and assembly", Retrovirology, 10() pp.136 ().
9. Koh LB et al, "Epoxy Cross-Linked Collagen and Collagen-Laminin Peptide Hydrogels as Corneal Substitutes", Journal of Functional Biomaterials, 4(3) pp.162-177 ().
10. Kolesanova EF et al, "Development of the Schedule for Multiple Parallel Difficult Peptide Synthesis on Pins", International Journal of Peptides, 2013() pp.197317 (2013).
11. Chang YS et al, "Stapled ?-helical peptide drug development: A potent dual inhibitor of MDM2 and MDMX for p53-dependent cancer therapy", Proceedings of the National Academy of Sciences of the United States of America, 110(36) pp.E3445-E3454 (2013 Sep 3).
12. Shen D et al, "Evaluation of Phage Display Discovered Peptides as Ligands for Prostate-Specific Membrane Antigen (PSMA)", PLoS ONE, 8(7) pp.e68339 ().
13. Tao H et al, "Engineered Nanostructured ?-Sheet Peptides Protect Membrane Proteins", Nature methods, 10(8) pp.759-761 (2013 Aug).
14. Koch CP et al, "Scrutinizing MHC-I Binding Peptides and Their Limits of Variation", PLoS Computational Biology, 9(6) pp.e1003088 (2013 Jun).
15. Ryan L et al, "Anti-antimicrobial Peptides: FOLDING-MEDIATED HOST DEFENSE ANTAGONISTS", The Journal of Biological Chemistry, 288(28) pp.20162-20172 (2013 Jul 12).
16. Riou P et al, "14-3-3 Proteins Interact with a Hybrid Prenyl-Phosphorylation Motif to Inhibit G Proteins", Cell, 153(3) pp.640-653 (2013 Apr 25).
17. Jones S et al, "Intracellular translocation and differential accumulation of cell-penetrating peptides in bovine spermatozoa: evaluation of efficient delivery vectors that do not compromise human sperm motility", Human Reproduction (Oxford, England), 28(7) pp.1874-1889 (2013 Jul).
18. Pillay K et al, "Amylin Uncovered: A Review on the Polypeptide Responsible for Type II Diabetes", BioMed Research International, 2013() pp.826706 (2013).
19. Abd-Elgaliel WR et al, "Pancreatic Cancer-Associated Cathepsin E as a Drug Activator", Journal of controlled release : official journal of the Controlled Release Society, 167(3) pp.221-227 (2013 May 10).
20. Yang TY et al, "A Multiple Reaction Monitoring (MRM) Method to Detect Bcr-Abl Kinase Activity in CML Using a Peptide Biosensor", PLoS ONE, 8(2) pp.e56627 ().
21. Lipchik AM et al, "Time-Resolved Luminescence Detection of Syk Kinase Activity Through Terbium Sensitization", Analytical chemistry, 85(5) pp.2582-2588 (2013 Mar 5).
22. Ghosh G et al, "Activity Assay of Epidermal Growth Factor Receptor Tyrosine Kinase Inhibitors in Triple-Negative Breast Cancer Cells Using Peptide-Conjugated Magnetic Beads", Assay and Drug Development Technologies, 11(1) pp.44-51 (2013 Feb).
23. Geurink PP et al, "Incorporation of Non-natural Amino Acids Improves Cell Permeability and Potency of Specific Inhibitors of Proteasome Trypsin-like Sites", Journal of medicinal chemistry, 56(3) pp.1262-1275 (2013 Feb 14).
24. Kar K et al, "?-hairpin-mediated nucleation of polyglutamine amyloid formation", Journal of molecular biology, 425(7) pp.1183-1197 (2013 Apr 12).
25. Shimko JC et al, "Preparing Semisynthetic and Fully Synthetic Histones H3 and H4 to Modify the Nucleosome Core", Methods in molecular biology (Clifton, N.J.), 981() pp.10.1007/978-1-62703-305-3_14 (2013).