- Description
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Nα-Fmoc-S-trityl-L-cysteine - Additional Information
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Additional Information
Catalog Number 41008 CAS 103213-32-7 M.W. 585.71 Formula C37H31NO4S IUPAC Name (2R)-2-(9H-fluoren-9-ylmethoxycarbonylamino)-3-tritylsulfanylpropanoic acid Synonym Nα-Fmoc-S-trityl-L-cysteine Also Known As - (2R)-2-(9H-fluoren-9-ylmethoxycarbonylamino)-3-[tri(phenyl)methylsulfanyl]propanoic acid
- (2R)-2-[(9H-fluoren-9-ylmethoxy-oxomethyl)amino]-3-[tri(phenyl)methylthio]propanoic acid
- (2R)-2-(9H-fluoren-9-ylmethoxycarbonylamino)-3-[tri(phenyl)methylthio]propionic acid
- Nalpha-Fmoc-S-trityl-L-cysteine
- 08503_FLUKA
- Fmoc-D-Cys(Trt)-OH
- Nalpha-Fmoc-S-trityl-D-cysteine
- Fmoc-S-trityl-cys
- L-Cysteine, N-((9H-fluoren-9-ylmethoxy)carbonyl)-S-(triphenylmethyl)-
- N(alpha)-Fluorenylmethyloxycarbonyl-S-tritylcysteine
- 47695_FLUKA
- Fmoc-Cys(Trt)-OH
- N-(9-Fluorenylmethoxycarbonyl)-S-trityl-L-cysteine
InChIKey KLBPUVPNPAJWHZ-UMSFTDKQSA-N InChI InChI=1S/C37H31NO4S/c39-35(40)34(38-36(41)42-24-33-31-22-12-10-20-29(31)30-21-11-13-23-32(30)33)25-43-37(26-14-4-1-5-15-26,27-16-6-2-7-17-27)28-18-8-3-9-19-28/h1-23,33-34H,24-25H2,(H,38,41)(H,39,40)/t34-/m0/s1 SMILES C1=CC=C(C=C1)C(C2=CC=CC=C2)(C3=CC=CC=C3)SC[C@@H](C(=O)O)NC(=O)OCC4C5=CC=CC=C5C6=CC=CC=C46 - Cited Uses
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Details
1. Anand P et al, "Sample Limited Characterization of a Novel Disulfide-Rich Venom Peptide Toxin from Terebrid Marine Snail Terebra variegata", PLoS ONE, 9(4) pp.e94122 ().2. Taha MS et al, "Subcellular Fractionation and Localization Studies Reveal a Direct Interaction of the Fragile X Mental Retardation Protein (FMRP) with Nucleolin", PLoS ONE, 9(3) pp.e91465 ().3. Witte MD et al, "Production of unnaturally linked chimeric proteins using a combination of sortase-catalyzed transpeptidation and click chemistry", Nature protocols, 8(9) pp.1808-1819 (2013 Sep).4. Guimaraes CP et al, "Site-specific C-terminal internal loop labeling of proteins using sortase-mediated reactions", Nature protocols, 8(9) pp.1787-1799 (2013 Sep).5. Theile CS et al, "Site-specific N-terminal labeling of proteins using sortase-mediated reactions", Nature protocols, 8(9) pp.1800-1807 (2013 Sep).6. Wissner RF et al, "Labeling Proteins with Fluorophore/Thioamide FRET Pairs by Combining Unnatural Amino Acid Mutagenesis and Native Chemical Ligation", Journal of the American Chemical Society, 135(17) pp.6529-6540 (2013 May 1).7. Ki CS et al, "Facile preparation of photodegradable hydrogels by photopolymerization", Polymer, 54(8) pp.2115-2122 (2013 Apr 3).8. Dadiboyena S et al, "Parallel Synthesis of Structurally Diverse Aminobenzimidazole Tethered Sultams and Benzothiazepinones", Tetrahedron letters, 53(51) pp.6897-6900 (2012 Dec 19).9. Wehner JW et al, "S-Fluorenylmethyl protection of the cysteine side chain upon N α-Fmoc deprotection", Beilstein Journal of Organic Chemistry, 8() pp.2149-2155 ().10. Gunasekera S et al, "Making Ends Meet: Microwave-Accelerated Synthesis of Cyclic and Disulfide Rich Proteins Via In Situ Thioesterification and Native Chemical Ligation", International Journal of Peptide Research and Therapeutics, 19(1) pp.43-54 (2013 Mar).11. Jo H et al, "Development of ?-Helical Calpain Probes by Mimicking a Natural Protein-Protein Interaction", Journal of the American Chemical Society, 134(42) pp.17704-17713 (2012 Oct 24).12. Huang J et al, "Residue analysis of a CTL epitope of SARS-CoV spike protein by IFN-gamma production and bioinformatics prediction", BMC Immunology, 13() pp.50 ().13. Lin X et al, "Evaluation of the association of mercury(II) with some dicysteinyl tripeptides", Bioorganic chemistry, 44() pp.8-18 (2012 Oct).14. Tatsi A et al, "[111In-DOTA]Somatostatin-14 analogs as potential pansomatostatin-like radiotracers - first results of a preclinical study", EJNMMI Research, 2() pp.25 ().15. Batjargal S et al, "Native Chemical Ligation of Thioamide-Containing Peptides: Development and Application to the Synthesis of Labeled ?-Synuclein for Misfolding Studies", Journal of the American Chemical Society, 134(22) pp.9172-9182 (2012 Jun 6).16. Mosco A et al, "Novel Protocol for the Chemical Synthesis of Crustacean Hyperglycemic Hormone Analogues -- An Efficient Experimental Tool for Studying Their Functions", PLoS ONE, 7(1) pp.e30052 ().17. Fehr F et al, "Semi-Synthesis and Analysis of Chemically Modified Zif268 Zinc-Finger Domains", ChemistryOpen, 1(1) pp.26-32 (2012 Feb).18. Rothbart SB et al, "Peptide Microarrays to Interrogate the Histone Code", Methods in enzymology, 512() pp.107-135 (2012).19. Lin CC et al, "PEG hydrogels formed by thiol-ene photo-click chemistry and their effect on the formation and recovery of insulin-secreting cell spheroids", Biomaterials, 32(36) pp.9685-9695 (2011 Dec).20. Li Y et al, "Well-defined, Reversible Disulfide Cross-linked Micelles for On-demand Paclitaxel Delivery", Biomaterials, 32(27) pp.6633-6645 (2011 Sep).21. Zhan K et al, "Real-Time Imaging of Rab5 Activity Using a Pre-Quenched Biosensor", ACS chemical biology, 6(7) pp.692-699 (2011 Jul 15).22. Nefzi A et al, "N-terminus 4-Chloromethyl Thiazole Peptide as a Macrocyclization Tool in the Synthesis of Cyclic Peptides: Application to the Synthesis of Conformationally Constrained RGD-Containing Integrin Ligands", Tetrahedron letters, 52(7) pp.817-819 (2011 Feb 16).23. Nefzi A et al, "Two-Steps Hantzsch Based Macrocyclization Approach for the Synthesis of Thiazole Containing Cyclopeptides", The Journal of organic chemistry, 75(22) pp.7939-7941 (2010 Nov 19).24. Gao W et al, "PEG with Observable Shedding", Angewandte Chemie (International ed. in English), 49(37) pp.6567-6571 (2010 Sep 3).25. Kaushansky A et al, "Quantifying protein-protein interactions in high throughput using protein domain microarrays", Nature protocols, 5(4) pp.773-790 (2010). - Reviews
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