- Description
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Details
(2S)-2-(9H-fluoren-9-ylmethoxycarbonylamino)-3-(4-hydroxyphenyl)propanoic acid - Additional Information
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Additional Information
Catalog Number 41107 CAS 92954-90-0 M.W. 403.43 Formula C24H21NO5 IUPAC Name (2S)-2-(9H-fluoren-9-ylmethoxycarbonylamino)-3-(4-hydroxyphenyl)propanoic acid Synonym No Also Known As - 47751_FLUKA
- Fmoc-Tyr-OH
- Nalpha-Fmoc-L-tyrosine
InChIKey SWZCTMTWRHEBIN-QFIPXVFZSA-N InChI InChI=1S/C24H21NO5/c26-16-11-9-15(10-12-16)13-22(23(27)28)25-24(29)30-14-21-19-7-3-1-5-17(19)18-6-2-4-8-20(18)21/h1-12,21-22,26H,13-14H2,(H,25,29)(H,27,28)/t22-/m0/s1 SMILES C1=CC=C2C(=C1)C(C3=CC=CC=C32)COC(=O)N[C@@H](CC4=CC=C(C=C4)O)C(=O)O - Cited Uses
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Details
1. White TR et al, "On-resin N-methylation of cyclic peptides for discovery of orally bioavailable scaffolds", Nature Chemical Biology, 7(11) pp.810-817 ().2. Yao N et al, "Facile synthesis of glycosylated Fmoc amino acid building blocks assisted by microwave irradiation", Carbohydrate research, 345(15) pp.2277-2281 (2010 Oct 13).3. Kim SH et al, "Heparin-mimetic sulfated peptides with modulated affinities for heparin-binding peptides and growth factors", Peptides, 28(11) pp.2125-2136 (2007 Nov).4. Stirnweiss J et al, "Tyr-c[D-Orn-Tyr(Bzl)-Pro-Gly]: a novel antiproliferative acting somatostatin receptor agonist with μ-opioid receptor-sensitizing properties", British Journal of Pharmacology, 140(1) pp.13-22 (2003 Sep).5. Yan X et al, "The specificity of the protein kinase C alpha, betaII and gamma isoforms as assessed by an unnatural alcohol-appended peptide library.", Biochemical Journal, 349(Pt 3) pp.709-715 (2000 Aug 1).6. Cho H et al, "Substrate specificities of catalytic fragments of protein tyrosine phosphatases (HPTP beta, LAR, and CD45) toward phosphotyrosylpeptide substrates and thiophosphotyrosylated peptides as inhibitors.", Protein Science : A Publication of the Protein Society, 2(6) pp.977-984 (1993 Jun). - Reviews
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